Detalhe da pesquisa
1.
An ancestral mycobacterial effector promotes dissemination of infection.
Cell
; 185(24): 4507-4525.e18, 2022 11 23.
Artigo
Inglês
| MEDLINE | ID: mdl-36356582
2.
Caspase-11 interaction with NLRP3 potentiates the noncanonical activation of the NLRP3 inflammasome.
Nat Immunol
; 23(5): 705-717, 2022 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35487985
3.
Pyroptosis in defense against intracellular bacteria.
Semin Immunol
; 69: 101805, 2023 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37429234
4.
Shigella IpaH9.8 limits GBP1-dependent LPS release from intracytosolic bacteria to suppress caspase-4 activation.
Proc Natl Acad Sci U S A
; 120(15): e2218469120, 2023 04 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37014865
5.
LPS-aggregating proteins GBP1 and GBP2 are each sufficient to enhance caspase-4 activation both in cellulo and in vitro.
Proc Natl Acad Sci U S A
; 120(15): e2216028120, 2023 04 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37023136
6.
SNX10 and caspase-5 sort out endosomal LPS for a gut-wrenching Slug-fest.
EMBO J
; 40(24): e110128, 2021 12 15.
Artigo
Inglês
| MEDLINE | ID: mdl-34796973
7.
Overexpression of T3SS translocation signals in Salmonella causes delayed attenuation.
Infect Immun
; 92(1): e0032923, 2024 Jan 16.
Artigo
Inglês
| MEDLINE | ID: mdl-38084951
8.
Direct binding of polymeric GBP1 to LPS disrupts bacterial cell envelope functions.
EMBO J
; 39(13): e104926, 2020 07 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32510692
9.
Differential Requirement for IRGM Proteins during Tuberculosis Infection in Mice.
Infect Immun
; 91(2): e0051022, 2023 02 16.
Artigo
Inglês
| MEDLINE | ID: mdl-36629440
10.
Mycobacterium tuberculosis Evasion of Guanylate Binding Protein-Mediated Host Defense in Mice Requires the ESX1 Secretion System.
Int J Mol Sci
; 24(3)2023 Feb 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36769182
11.
Dynamin-related Irgm proteins modulate LPS-induced caspase-11 activation and septic shock.
EMBO Rep
; 21(11): e50830, 2020 11 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33124745
12.
Murine Irgm Paralogs Regulate Nonredundant Functions To Execute Host Defense to Toxoplasma gondii.
Infect Immun
; 89(11): e0020221, 2021 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-34338548
13.
Galectin-3 directs antimicrobial guanylate binding proteins to vacuoles furnished with bacterial secretion systems.
Proc Natl Acad Sci U S A
; 114(9): E1698-E1706, 2017 02 28.
Artigo
Inglês
| MEDLINE | ID: mdl-28193861
14.
Crohn's disease IRGM risk alleles are associated with altered gene expression in human tissues.
Am J Physiol Gastrointest Liver Physiol
; 316(1): G95-G105, 2019 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30335469
15.
Metabolic Alterations Contribute to Enhanced Inflammatory Cytokine Production in Irgm1-deficient Macrophages.
J Biol Chem
; 292(11): 4651-4662, 2017 03 17.
Artigo
Inglês
| MEDLINE | ID: mdl-28154172
16.
The Listeria monocytogenes PASTA Kinase PrkA and Its Substrate YvcK Are Required for Cell Wall Homeostasis, Metabolism, and Virulence.
PLoS Pathog
; 12(11): e1006001, 2016 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-27806131
17.
Sweet host revenge: Galectins and GBPs join forces at broken membranes.
Cell Microbiol
; 19(12)2017 12.
Artigo
Inglês
| MEDLINE | ID: mdl-28973783
18.
Ubiquitin systems mark pathogen-containing vacuoles as targets for host defense by guanylate binding proteins.
Proc Natl Acad Sci U S A
; 112(41): E5628-37, 2015 Oct 13.
Artigo
Inglês
| MEDLINE | ID: mdl-26417105
19.
Guanylate Binding Proteins Regulate Inflammasome Activation in Response to Hyperinjected Yersinia Translocon Components.
Infect Immun
; 85(10)2017 10.
Artigo
Inglês
| MEDLINE | ID: mdl-28784930
20.
Human GBP1 does not localize to pathogen vacuoles but restricts Toxoplasma gondii.
Cell Microbiol
; 18(8): 1056-64, 2016 08.
Artigo
Inglês
| MEDLINE | ID: mdl-26874079